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Guido Bocci Selected Research

Pharmaceutical Preparations

1/2022A 5-Year Study of Lithium and Valproic Acid Drug Monitoring in Patients with Bipolar Disorders in an Italian Clinical Center.
1/2019Chemotherapeutic and antiangiogenic drugs beyond tumor progression in colon cancer: Evaluation of the effects of switched schedules and related pharmacodynamics.
1/2019Dual Kit/Aur Inhibitors as Chemosensitizing Agents for the Treatment of Melanoma: Design, Synthesis, Docking Studies and Functional Investigation.
6/2018Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.
12/2015Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer.
1/2015Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs.
9/2013Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.
5/2012The possible role of chemotherapy in antiangiogenic drug resistance.
1/2012Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity.
6/2011Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells.
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Guido Bocci Research Topics

Disease

54Neoplasms (Cancer)
01/2022 - 05/2002
16Breast Neoplasms (Breast Cancer)
03/2022 - 05/2002
13Colorectal Neoplasms (Colorectal Cancer)
01/2018 - 02/2004
11Anaplastic Thyroid Carcinoma
02/2020 - 04/2012
10Thyroid Neoplasms (Thyroid Cancer)
01/2020 - 03/2007
9Glioblastoma (Glioblastoma Multiforme)
01/2022 - 01/2018
7Prostatic Neoplasms (Prostate Cancer)
12/2016 - 08/2009
7Macular Degeneration (Age-Related Maculopathy)
01/2016 - 01/2007
4Drug-Related Side Effects and Adverse Reactions
01/2022 - 01/2004
4Carcinoma (Carcinomatosis)
05/2021 - 10/2004
4Neoplasm Metastasis (Metastasis)
01/2017 - 02/2004
3Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2022 - 10/2011
3Gastrointestinal Neoplasms (Gastrointestinal Cancer)
02/2021 - 10/2006
3Colonic Neoplasms (Colon Cancer)
01/2020 - 08/2017
3Lymphoma (Lymphomas)
12/2018 - 10/2011
3Pancreatic Neoplasms (Pancreatic Cancer)
09/2012 - 09/2004
3Endometriosis
12/2010 - 11/2003
2Seizures (Absence Seizure)
01/2022 - 01/2022
2Brain Neoplasms (Brain Tumor)
01/2022 - 12/2012
2Melanoma (Melanoma, Malignant)
01/2019 - 10/2005
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 02/2016
2Triple Negative Breast Neoplasms
01/2016 - 12/2015
2medullary Thyroid cancer
11/2014 - 02/2014
2Hepatocellular Carcinoma (Hepatoma)
01/2014 - 11/2006
2Infections
09/2013 - 04/2010
2Pre-Eclampsia (Preeclampsia)
02/2013 - 06/2004
2Neutropenia
12/2011 - 05/2002
1Bipolar Disorder (Manic Depressive Psychosis)
01/2022
1Inflammation (Inflammations)
01/2022
1Lewis Lung Carcinoma
05/2021
1Glioma (Gliomas)
01/2021

Drug/Important Bio-Agent (IBA)

22Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2022 - 09/2004
18Pharmaceutical PreparationsIBA
01/2022 - 05/2002
12Fluorouracil (Carac)FDA LinkGeneric
02/2021 - 06/2005
10Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2022 - 10/2003
10Irinotecan (Camptosar)FDA LinkGeneric
01/2020 - 09/2006
10Tyrosine Kinase InhibitorsIBA
01/2018 - 09/2004
8Bevacizumab (Avastin)FDA Link
03/2022 - 05/2007
7Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
03/2022 - 09/2004
7Paclitaxel (Taxol)FDA LinkGeneric
03/2022 - 05/2002
6Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2004
6Vinorelbine (Navelbine)FDA LinkGeneric
05/2021 - 02/2016
6Antineoplastic Agents (Antineoplastics)IBA
01/2020 - 10/2005
5ErbB Receptors (EGF Receptor)IBA
07/2016 - 09/2013
5Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
07/2016 - 09/2004
5pyrimidineIBA
07/2016 - 02/2011
5Proteins (Proteins, Gene)FDA Link
02/2014 - 10/2005
4Thrombospondin 1IBA
03/2022 - 10/2003
4Interleukin-8 (Interleukin 8)IBA
03/2022 - 12/2014
4Sunitinib (Sutent)FDA Link
01/2019 - 05/2012
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2018 - 09/2004
3Anticonvulsants (Antiepileptic Drugs)IBA
01/2022 - 01/2020
3Temozolomide (Temodar)FDA LinkGeneric
01/2022 - 06/2018
3Celecoxib (Celebrex)FDA Link
02/2021 - 08/2009
3LigandsIBA
01/2020 - 06/2004
3AntibodiesIBA
01/2019 - 11/2005
3pazopanibFDA Link
01/2019 - 04/2015
3Topotecan (Hycamtin)FDA LinkGeneric
01/2019 - 04/2015
3GemcitabineFDA Link
01/2017 - 09/2004
3Biological ProductsIBA
11/2005 - 11/2003
2Valproic Acid (Depakote)FDA LinkGeneric
01/2022 - 01/2022
2Alkylating AgentsIBA
01/2022 - 10/2005
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2022 - 01/2021
2ProdrugsIBA
01/2022 - 02/2021
2lenvatinibIBA
01/2020 - 05/2018
2Hormones (Hormone)IBA
01/2019 - 08/2009
2Phosphotransferases (Kinase)IBA
01/2019 - 02/2014
2MelanocortinsIBA
06/2018 - 01/2018
2CalciumIBA
08/2017 - 01/2006
2Cisplatin (Platino)FDA LinkGeneric
01/2017 - 10/2005
2Dexamethasone (Maxidex)FDA LinkGeneric
12/2016 - 08/2009
2Ranibizumab (Lucentis)FDA Link
01/2016 - 04/2013
24- chloro- N- (1,1,3- trioxo- 2,3- dihydrobenzo(d)isothiazol- 4- yl)benzamideIBA
11/2014 - 04/2012
2AmidesIBA
11/2014 - 04/2012
2Messenger RNA (mRNA)IBA
09/2013 - 11/2006
2DaptomycinFDA Link
09/2013 - 04/2010
2Cyclin D1IBA
09/2012 - 06/2011
2Monoclonal AntibodiesIBA
05/2012 - 09/2004
2Endothelial Growth FactorsIBA
02/2011 - 05/2002
2Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2009 - 09/2006
2DNA (Deoxyribonucleic Acid)IBA
08/2009 - 10/2005
2Leucovorin (Folinic Acid)FDA Link
10/2006 - 09/2006
1LithiumIBA
01/2022
1Histone Deacetylase InhibitorsIBA
01/2022
1Levetiracetam (Keppra)FDA LinkGeneric
01/2022
1Phenobarbital (Luminal)FDA Link
01/2022
1Phenytoin (Dilantin)FDA LinkGeneric
01/2022
1Carbamazepine (Tegretol)FDA LinkGeneric
01/2022
1IfosfamideFDA LinkGeneric
01/2022
1Busulfan (Busulfex)FDA Link
01/2022
1Interleukin-2 (IL2)IBA
05/2021
1Interferon-gamma (Interferon, gamma)IBA
02/2021
1CytokinesIBA
02/2021

Therapy/Procedure

27Drug Therapy (Chemotherapy)
01/2022 - 09/2006
19Therapeutics
01/2022 - 05/2002
3Radiotherapy
11/2021 - 01/2015
3Castration
12/2016 - 05/2010
2Heterologous Transplantation (Xenotransplantation)
08/2014 - 02/2011
2Breast Implants (Breast Implant)
01/2014 - 10/2011
1Chemoradiotherapy
01/2022